isotanshinone I

Modify Date: 2024-01-08 17:52:09

isotanshinone I Structure
isotanshinone I structure
Common Name isotanshinone I
CAS Number 20958-17-2 Molecular Weight 276.28600
Density 1.324±0.06 g/cm3 Boiling Point 495.8±34.0 °C at 760 mmHg
Molecular Formula C18H12O3 Melting Point 219 ºC
MSDS N/A Flash Point N/A

 Use of isotanshinone I


Isotanshinone I has inhibitory activity against α-glucosidase and formation of AGE, with IC50s of 1.13, 0.432 μM for α-glucosidase and AGE, respectively.

 Names

Name isotanshinone I
Synonym More Synonyms

 isotanshinone I Biological Activity

Description Isotanshinone I has inhibitory activity against α-glucosidase and formation of AGE, with IC50s of 1.13, 0.432 μM for α-glucosidase and AGE, respectively.
Related Catalog
Target

IC50: 1.13μM (α-glucosidase), 0.432 μM (AGE)[1].

References

[1]. Ma HY, et al. Constituents with α-glucosidase and advanced glycation end-product formation inhibitory activities from Salvia miltiorrhiza Bge. J Nat Med. 2011 Jan;65(1):37-42.

 Chemical & Physical Properties

Density 1.324±0.06 g/cm3
Boiling Point 495.8±34.0 °C at 760 mmHg
Melting Point 219 ºC
Molecular Formula C18H12O3
Molecular Weight 276.28600
Exact Mass 276.07900
PSA 47.28000
LogP 3.82500
Water Solubility Insuluble (2.1E-5 g/L) (25 ºC)

 Synonyms

Isotanshinon-I
4,8-Dimethylphenanthro[3,2-b]furan-7,11-dione
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