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20958-15-0

20958-15-0 structure
20958-15-0 structure
  • Name: Isotanshinone IIA
  • Chemical Name: isotanshinone IIA
  • CAS Number: 20958-15-0
  • Molecular Formula: C19H18O3
  • Molecular Weight: 294.34400
  • Catalog: Signaling Pathways Metabolic Enzyme/Protease Phosphatase
  • Create Date: 2018-07-03 14:31:18
  • Modify Date: 2025-08-25 12:33:51
  • Isotanshinone IIA, an abietane-type diterpene metabolite, could non-competitively inhibit Protein Tyrosine Phosphatase 1B (PTP1B) activity with an IC50 0f 11.4 μM.

Name isotanshinone IIA
Synonyms 4,4,8-Trimethyl-2,3-dihydro-1H,4H-10-oxa-cyclopenta[b]phenanthrene-7,11-dione
Isotanshinon-II
isotanshinone II
Description Isotanshinone IIA, an abietane-type diterpene metabolite, could non-competitively inhibit Protein Tyrosine Phosphatase 1B (PTP1B) activity with an IC50 0f 11.4 μM.
Related Catalog
Target

IC50: 11.4 μM (PTP1B)[1].

References

[1]. Han YM, et al. PTP1B inhibitory effect of abietane diterpenes isolated from Salvia miltiorrhiza. Biol Pharm Bull. 2005 Sep;28(9):1795-7.

Boiling Point 471.1±45.0 °C(Predicted)
Molecular Formula C19H18O3
Molecular Weight 294.34400
Exact Mass 294.12600
PSA 47.28000
LogP 3.97730
Hazard Codes Xi
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