Hydroxy-PEG5-C2-methyl ester

Modify Date: 2024-01-12 21:03:29

Hydroxy-PEG5-C2-methyl ester Structure
Hydroxy-PEG5-C2-methyl ester structure
Common Name Hydroxy-PEG5-C2-methyl ester
CAS Number 2100306-80-5 Molecular Weight 440.53
Density N/A Boiling Point N/A
Molecular Formula C14H28O8 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Hydroxy-PEG5-C2-methyl ester


Hydroxy-PEG5-C2-methyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Hydroxy-PEG5-methyl ester
Synonym More Synonyms

 Hydroxy-PEG5-C2-methyl ester Biological Activity

Description Hydroxy-PEG5-C2-methyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C14H28O8
Molecular Weight 440.53

 Synonyms

MFCD30730370
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