2-Hydroxy-5-(trifluoromethyl)benzaldehyde

Modify Date: 2024-01-02 21:04:33

2-Hydroxy-5-(trifluoromethyl)benzaldehyde Structure
2-Hydroxy-5-(trifluoromethyl)benzaldehyde structure
Common Name 2-Hydroxy-5-(trifluoromethyl)benzaldehyde
CAS Number 210039-65-9 Molecular Weight 190.119
Density 1.4±0.1 g/cm3 Boiling Point 204.5±35.0 °C at 760 mmHg
Molecular Formula C8H5F3O2 Melting Point N/A
MSDS N/A Flash Point 77.5±25.9 °C

 Names

Name 2-hydroxy-5-(trifluoromethyl)benzaldehyde
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 204.5±35.0 °C at 760 mmHg
Molecular Formula C8H5F3O2
Molecular Weight 190.119
Flash Point 77.5±25.9 °C
Exact Mass 190.024170
PSA 37.30000
LogP 3.21
Vapour Pressure 0.2±0.4 mmHg at 25°C
Index of Refraction 1.511
Storage condition 2-8°C

 Synthetic Route

~33%

2-Hydroxy-5-(trifluoromethyl)benzaldehyde Structure

2-Hydroxy-5-(tr...

CAS#:210039-65-9

Literature: Lin, Xu; Doyle, Terrence W.; King, Ivan Patent: US2004/254103 A1, 2004 ; Location in patent: Page 9 ;

~%

2-Hydroxy-5-(trifluoromethyl)benzaldehyde Structure

2-Hydroxy-5-(tr...

CAS#:210039-65-9

Literature: NSAB, FILIAL AF NEUROSEARCH SWEDEN AB, SVERIGE Patent: WO2009/133109 A1, 2009 ; Location in patent: Page/Page column 54 ;

~77%

2-Hydroxy-5-(trifluoromethyl)benzaldehyde Structure

2-Hydroxy-5-(tr...

CAS#:210039-65-9

Literature: Geneste; Schaefer Synthesis, 2001 , # 15 p. 2259 - 2262

~%

2-Hydroxy-5-(trifluoromethyl)benzaldehyde Structure

2-Hydroxy-5-(tr...

CAS#:210039-65-9

Literature: SUMITOMO CHEMICAL COMPANY, LIMITED; Iwakoshi, Mitsuhiko; Takyo, Hayato Patent: US2013/90353 A1, 2013 ; Location in patent: Paragraph 0739 ;

~30%

2-Hydroxy-5-(trifluoromethyl)benzaldehyde Structure

2-Hydroxy-5-(tr...

CAS#:210039-65-9

Literature: Achard, Thierry; Belokon', Yuri N.; Fuentes, Jose A.; North, Michael; Parsons, Teresa Tetrahedron, 2004 , vol. 60, # 28 p. 5919 - 5930

~%

2-Hydroxy-5-(trifluoromethyl)benzaldehyde Structure

2-Hydroxy-5-(tr...

CAS#:210039-65-9

Literature: ASTRAZENECA AB; ASTRAZENECA UK LIMITED Patent: WO2006/56752 A1, 2006 ; Location in patent: Page/Page column 31 ; WO 2006/056752 A1

~68%

2-Hydroxy-5-(trifluoromethyl)benzaldehyde Structure

2-Hydroxy-5-(tr...

CAS#:210039-65-9

Literature: Samant, Bhupesh S.; Kabalka, George W. Chemical Communications, 2011 , vol. 47, # 25 p. 7236 - 7238

~%

2-Hydroxy-5-(trifluoromethyl)benzaldehyde Structure

2-Hydroxy-5-(tr...

CAS#:210039-65-9

Literature: Belokon', Yuri N.; Davies; Fuentes, Jose A.; North, Michael; Parsons, Teresa Tetrahedron Letters, 2001 , vol. 42, # 45 p. 8093 - 8096

 Synonyms

5-trifluoromethyl-2-hydroxybenzaldehyde
2-hydroxy-4-trifluoromethyl benzaldehyde
2-Hydroxy-5-(trifluoromethyl)benzaldehyde
2-hydroxy-5-trifluoromethylbenzaldehyde
Benzaldehyde, 2-hydroxy-5-(trifluoromethyl)-
5-trifluoromethylsalicylaldehyde