EML-633

Modify Date: 2023-01-14 17:06:44

EML-633 Structure
EML-633 structure
Common Name EML-633
CAS Number 2101954-85-0 Molecular Weight 682.998
Density N/A Boiling Point N/A
Molecular Formula C42H62N6O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of EML-633


A small-molecule inhibitor of Spindlin1 (SPIN1) with Kd of 2 uM; shows increased selectivity and engages SPIN1 in cells, block its ability to 'read' H3K4me3 marks and inhibit its transcriptional-coactivator activity.

 Names

Name EML-633

 EML-633 Biological Activity

Description A small-molecule inhibitor of Spindlin1 (SPIN1) with Kd of 2 uM; shows increased selectivity and engages SPIN1 in cells, block its ability to 'read' H3K4me3 marks and inhibit its transcriptional-coactivator activity.
References References 1. Bae N, et al. Nat Chem Biol. 2017 May 15. doi: 10.1038/nchembio.2377. 2. Wang W, et al. EMBO Rep. 2011 Oct 28;12(11):1160-6. View Related Products by Target Other Targets

 Chemical & Physical Properties

Molecular Formula C42H62N6O2
Molecular Weight 682.998