Dihomo-γ-Linolenic acid methyl ester

Modify Date: 2025-08-24 14:22:34

Dihomo-γ-Linolenic acid methyl ester Structure
Dihomo-γ-Linolenic acid methyl ester structure
Common Name Dihomo-γ-Linolenic acid methyl ester
CAS Number 21061-10-9 Molecular Weight 320.509
Density 0.9±0.1 g/cm3 Boiling Point 405.0±24.0 °C at 760 mmHg
Molecular Formula C21H36O2 Melting Point N/A
MSDS Chinese USA Flash Point 99.6±21.2 °C
Symbol GHS02 GHS07
GHS02, GHS07
Signal Word Danger

 Use of Dihomo-γ-Linolenic acid methyl ester


Dihomo-γ-Linolenic acid is an n-6 polyunsaturated fatty acid that is mainly metabolized to an anti-inflammatory eicosanoid, prostaglandin (PG) E1, via the cyclooxygenase (COX) pathway. Anti-inflammatory and anti-proliferative effects[1][2].

 Names

Name cis-8,11,14-Eicosatrienoic acid methyl ester
Synonym More Synonyms

 Dihomo-γ-Linolenic acid methyl ester Biological Activity

Description Dihomo-γ-Linolenic acid is an n-6 polyunsaturated fatty acid that is mainly metabolized to an anti-inflammatory eicosanoid, prostaglandin (PG) E1, via the cyclooxygenase (COX) pathway. Anti-inflammatory and anti-proliferative effects[1][2].
Related Catalog
References

[1]. Takai S, et al. Anti-atherosclerotic effects of dihomo-gamma-linolenic acid in ApoE-deficient mice. J Atheroscler Thromb. 2009;16(4):480-489.

[2]. Chutrakul C, et al. Metabolic engineering of long chain-polyunsaturated fatty acid biosynthetic pathway in oleaginous fungus for dihomo-gamma linolenic acid production. J Biotechnol. 2016;218:85-93.

 Chemical & Physical Properties

Density 0.9±0.1 g/cm3
Boiling Point 405.0±24.0 °C at 760 mmHg
Molecular Formula C21H36O2
Molecular Weight 320.509
Flash Point 99.6±21.2 °C
Exact Mass 320.271515
PSA 26.30000
LogP 8.02
Appearance of Characters Liquid
Vapour Pressure 0.0±0.9 mmHg at 25°C
Index of Refraction 1.475
InChIKey QHATYOWJCAQINT-JPFHKJGASA-N
SMILES CCCCCC=CCC=CCC=CCCCCCCC(=O)OC
Storage condition −20°C

 Safety Information

Symbol GHS02 GHS07
GHS02, GHS07
Signal Word Danger
Hazard Statements H225-H319
Precautionary Statements P210-P280-P305 + P351 + P338-P337 + P313-P403 + P235
Personal Protective Equipment Eyeshields;Gloves
RIDADR UN1170 - class 3 - PG 2 - Ethanol, solution
WGK Germany 3
HS Code 2916190090

 Customs

HS Code 2916190090
Summary 2916190090 unsaturated acyclic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives。supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward)。VAT:17.0%。tax rebate rate:9.0%。MFN tariff:6.5%。general tariff:30.0%

 Dihomo-γ-Linolenic acid methyl esterBioassay

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Name: Discovery of Small Molecules to Inhibit Human Cytomegalovirus Nuclear Egress
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
Target: HCMV UL50
External Id: HMS1262
Name: A screen for small molecules that modulate mitochondrial supercomplex formation
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
Target: N/A
External Id: HMS1482
Name: Cell-based high throughput primary assay to identify activators of GPR151
Source: The Scripps Research Institute Molecular Screening Center
Target: RecName: Full=G-protein coupled receptor 151; AltName: Full=G-protein coupled receptor PGR7; AltName: Full=GPCR-2037; AltName: Full=Galanin receptor 4; AltName: Full=Galanin-receptor-like protein; Short=GalRL
External Id: GPR151_PHUNTER_AG_LUMI_1536_1X%ACT
Name: AlphaScreen-based biochemical high throughput primary assay to identify inhibitors of...
Source: The Scripps Research Institute Molecular Screening Center
External Id: MITF_INH_Alpha_1536_1X%INH PRUN
Name: Stabilization of p53 in human papillomavirus-positive cells
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
Target: Cellular tumor antigen p53
External Id: HMS1485
Name: Discovering small molecule activators of G protein-gated inwardly-rectifying potassiu...
Source: 15621
Target: G protein-activated inward rectifier potassium channel 2
External Id: VANDERBILT_HTS_GIRK2_MPD
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 Synonyms

Methyl (8Z,11Z,14Z)-icosa-8,11,14-trienoate
Methyl (8Z,11Z,14Z)-8,11,14-icosatrienoate
methyl icosa-8,11,14-trienoate
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