N-(m-PEG4)-N'-(PEG4-NHS ester)-Cy5

Modify Date: 2024-01-09 19:22:39

N-(m-PEG4)-N'-(PEG4-NHS ester)-Cy5 Structure
N-(m-PEG4)-N'-(PEG4-NHS ester)-Cy5 structure
Common Name N-(m-PEG4)-N'-(PEG4-NHS ester)-Cy5
CAS Number 2107273-30-1 Molecular Weight 926.53
Density N/A Boiling Point N/A
Molecular Formula C49H68ClN3O12 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of N-(m-PEG4)-N'-(PEG4-NHS ester)-Cy5


N-(m-PEG4)-N'-(PEG4-NHS ester)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name N-(m-PEG4)-N'-(PEG4-NHS ester)-Cy5

 N-(m-PEG4)-N'-(PEG4-NHS ester)-Cy5 Biological Activity

Description N-(m-PEG4)-N'-(PEG4-NHS ester)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C49H68ClN3O12
Molecular Weight 926.53

 Safety Information

Hazard Codes Xi
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