N-methyl-N'-methyl-O-(m-PEG4)-O'-(azide-PEG4)-Cy5

Modify Date: 2024-01-05 00:17:37

N-methyl-N'-methyl-O-(m-PEG4)-O'-(azide-PEG4)-Cy5 Structure
N-methyl-N'-methyl-O-(m-PEG4)-O'-(azide-PEG4)-Cy5 structure
Common Name N-methyl-N'-methyl-O-(m-PEG4)-O'-(azide-PEG4)-Cy5
CAS Number 2107273-56-1 Molecular Weight 886.51
Density N/A Boiling Point N/A
Molecular Formula C46H68ClN5O10 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of N-methyl-N'-methyl-O-(m-PEG4)-O'-(azide-PEG4)-Cy5


N-methyl-N'-methyl-O-(m-PEG4)-O'-(azide-PEG4)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name N-methyl-N'-methyl-O-(m-PEG4)-O'-(azide-PEG4)-Cy5

  Biological Activity

Description N-methyl-N'-methyl-O-(m-PEG4)-O'-(azide-PEG4)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C46H68ClN5O10
Molecular Weight 886.51

 Safety Information

Hazard Codes Xi