N-Methyl-N'-methyl-O-(m-PEG4)-O'-(azide-PEG4)-Cy3

Modify Date: 2024-01-10 17:39:32

N-Methyl-N'-methyl-O-(m-PEG4)-O'-(azide-PEG4)-Cy3 Structure
N-Methyl-N'-methyl-O-(m-PEG4)-O'-(azide-PEG4)-Cy3 structure
Common Name N-Methyl-N'-methyl-O-(m-PEG4)-O'-(azide-PEG4)-Cy3
CAS Number 2107273-64-1 Molecular Weight 860.48
Density N/A Boiling Point N/A
Molecular Formula C44H66ClN5O10 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of N-Methyl-N'-methyl-O-(m-PEG4)-O'-(azide-PEG4)-Cy3


N-Methyl-N'-methyl-O-(m-PEG4)-O'-(azide-PEG4)-Cy3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name N-Methyl-N'-methyl-O-(m-PEG4)-O'-(azide-PEG4)-Cy3

  Biological Activity

Description N-Methyl-N'-methyl-O-(m-PEG4)-O'-(azide-PEG4)-Cy3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

 Chemical & Physical Properties

Molecular Formula C44H66ClN5O10
Molecular Weight 860.48

 Safety Information

Hazard Codes Xi