N,N'-bis-(azide-PEG3)-chlorocyclohexenyl Cy7

Modify Date: 2024-01-09 13:49:35

N,N'-bis-(azide-PEG3)-chlorocyclohexenyl Cy7 structure	Common Name	N,N'-bis-(azide-PEG3)-chlorocyclohexenyl Cy7
	CAS Number	2107273-84-5	Molecular Weight	893.94
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₄₆H₆₂Cl₂N₈O₆	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of N,N'-bis-(azide-PEG3)-chlorocyclohexenyl Cy7

N,N'-bis-(azide-PEG3)-chlorocyclohexenyl Cy7 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	N,N'-bis-(azide-PEG3)-chlorocyclohexenyl Cy7

Description	N,N'-bis-(azide-PEG3)-chlorocyclohexenyl Cy7 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₄₆H₆₂Cl₂N₈O₆
Molecular Weight	893.94