2226235-96-5

2226235-96-5 structure

2226235-96-5 structure

Name: N-PEG3-N'-(azide-PEG3)-Cy5
Chemical Name: N-PEG3-N'-(azide-PEG3)-Cy5
CAS Number: 2226235-96-5
Molecular Formula: C₃₉H₅₄ClN₅O₆
Molecular Weight: 724.33
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-02 07:18:14
Modify Date: 2024-01-10 09:14:52
N-PEG3-N'-(azide-PEG3)-Cy5 (chloride) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	N-PEG3-N'-(azide-PEG3)-Cy5

Description	N-PEG3-N'-(azide-PEG3)-Cy5 (chloride) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₃₉H₅₄ClN₅O₆
Molecular Weight	724.33

Hazard Codes	Xi