N-(Ac-PEG3)-N'-(azide-PEG3)-Cy7 chloride

Modify Date: 2024-01-05 22:41:01

N-(Ac-PEG3)-N'-(azide-PEG3)-Cy7 chloride Structure
N-(Ac-PEG3)-N'-(azide-PEG3)-Cy7 chloride structure
Common Name N-(Ac-PEG3)-N'-(azide-PEG3)-Cy7 chloride
CAS Number 2107273-00-5 Molecular Weight 792.40
Density N/A Boiling Point N/A
Molecular Formula C43H58ClN5O7 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of N-(Ac-PEG3)-N'-(azide-PEG3)-Cy7 chloride


N-(Ac-PEG3)-N'-(azide-PEG3)-Cy7 (chloride) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name N-(Ac-PEG3)-N'-(azide-PEG3)-Cy7 chloride

 N-(Ac-PEG3)-N'-(azide-PEG3)-Cy7 chloride Biological Activity

Description N-(Ac-PEG3)-N'-(azide-PEG3)-Cy7 (chloride) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C43H58ClN5O7
Molecular Weight 792.40

 Safety Information

Hazard Codes Xi
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