N-(Azido-PEG3)-N-Boc-PEG3-t-butyl ester

Modify Date: 2024-01-09 14:33:13

N-(Azido-PEG3)-N-Boc-PEG3-t-butyl ester Structure
N-(Azido-PEG3)-N-Boc-PEG3-t-butyl ester structure
Common Name N-(Azido-PEG3)-N-Boc-PEG3-t-butyl ester
CAS Number 2112732-03-1 Molecular Weight 578.70
Density N/A Boiling Point N/A
Molecular Formula C26H50N4O10 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of N-(Azido-PEG3)-N-Boc-PEG3-t-butyl ester


N-(Azido-PEG3)-N-Boc-PEG3-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name N-(Azido-PEG3)-N-Boc-PEG3-t-butyl ester

 N-(Azido-PEG3)-N-Boc-PEG3-t-butyl ester Biological Activity

Description N-(Azido-PEG3)-N-Boc-PEG3-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C26H50N4O10
Molecular Weight 578.70

 Safety Information

Hazard Codes Xi