TLR7/8 agonist 6

Modify Date: 2024-01-15 17:36:47

TLR7/8 agonist 6 Structure
TLR7/8 agonist 6 structure
Common Name TLR7/8 agonist 6
CAS Number 2115702-83-3 Molecular Weight 417.50
Density N/A Boiling Point N/A
Molecular Formula C24H27N5O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of TLR7/8 agonist 6


TLR7/8 agonist 6 (Compound 4) is the potent agonist of TLR7/8 with IC50s of 0.18 and 5.34 μM, respectively. TLR7/8 agonist 6 is an imidazoquinoline derivative compound. Toll-like receptors (TLRs) 7 and 8 are key targets in the development of immunomodulatory drugs for treating infectious disease, cancer, and autoimmune disorders[1].

 Names

Name TLR7/8 agonist 6

 TLR7/8 agonist 6 Biological Activity

Description TLR7/8 agonist 6 (Compound 4) is the potent agonist of TLR7/8 with IC50s of 0.18 and 5.34 μM, respectively. TLR7/8 agonist 6 is an imidazoquinoline derivative compound. Toll-like receptors (TLRs) 7 and 8 are key targets in the development of immunomodulatory drugs for treating infectious disease, cancer, and autoimmune disorders[1].
Related Catalog
References

[1]. Yang M, et al. Toll-like receptor 7 and 8 imidazoquinoline-based agonist/antagonist pairs. Bioorg Med Chem Lett. 2022;59:128548.

 Chemical & Physical Properties

Molecular Formula C24H27N5O2
Molecular Weight 417.50