(S,R,S)-AHPC-PEG3-propionic acid

Modify Date: 2024-01-11 05:56:19

(S,R,S)-AHPC-PEG3-propionic acid Structure
(S,R,S)-AHPC-PEG3-propionic acid structure
Common Name (S,R,S)-AHPC-PEG3-propionic acid
CAS Number 2140807-42-5 Molecular Weight 662.79
Density N/A Boiling Point N/A
Molecular Formula C32H46N4O9S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of (S,R,S)-AHPC-PEG3-propionic acid


(S,R,S)-AHPC-PEG3-propionic acid is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 3-unit PEG linker used in PROTAC technology[1].

 Names

Name (S,R,S)-AHPC-PEG3-propionic acid

 (S,R,S)-AHPC-PEG3-propionic acid Biological Activity

Description (S,R,S)-AHPC-PEG3-propionic acid is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 3-unit PEG linker used in PROTAC technology[1].
Related Catalog
Target

VHL

References

[1]. Chan KH, et al. Impact of Target Warhead and Linkage Vector on Inducing Protein Degradation: Comparison of Bromodomain and Extra-Terminal (BET) Degraders Derived from Triazolodiazepine (JQ1) and Tetrahydroquinoline (I-BET726) BET Inhibitor Scaffolds. J Med Chem. 2018 Jan 25;61(2):504-513.

 Chemical & Physical Properties

Molecular Formula C32H46N4O9S
Molecular Weight 662.79

 Safety Information

Hazard Codes Xi
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