H-Gly-Phe-βNA

Modify Date: 2024-01-05 13:23:59

H-Gly-Phe-βNA Structure
H-Gly-Phe-βNA structure
Common Name H-Gly-Phe-βNA
CAS Number 21438-66-4 Molecular Weight 347.41000
Density 1.254g/cm3 Boiling Point 692.4ºC at 760mmHg
Molecular Formula C21H21N3O2 Melting Point N/A
MSDS Chinese USA Flash Point 372.6ºC
Symbol GHS08
GHS08
Signal Word Warning

 Use of H-Gly-Phe-βNA


Gly-Phe-β-naphthylamide is the substrate of Cathepsin C. Gly-Phe-β-naphthylamide can be used to study intralysosomal hydrolysis, lysosomal membrane permeability, and the function of cathepsin C[1].

 Names

Name Gly-Phe β-naphthylamide
Synonym More Synonyms

 H-Gly-Phe-βNA Biological Activity

Description Gly-Phe-β-naphthylamide is the substrate of Cathepsin C. Gly-Phe-β-naphthylamide can be used to study intralysosomal hydrolysis, lysosomal membrane permeability, and the function of cathepsin C[1].
Related Catalog
References

[1]. Baumgartner HK, et, al. Caspase-8-mediated apoptosis induced by oxidative stress is independent of the intrinsic pathway and dependent on cathepsins. Am J Physiol Gastrointest Liver Physiol. 2007 Jul;293(1):G296-307.

 Chemical & Physical Properties

Density 1.254g/cm3
Boiling Point 692.4ºC at 760mmHg
Molecular Formula C21H21N3O2
Molecular Weight 347.41000
Flash Point 372.6ºC
Exact Mass 347.16300
PSA 84.22000
LogP 3.62870
Vapour Pressure 5.04E-19mmHg at 25°C
Index of Refraction 1.673

 Safety Information

Symbol GHS08
GHS08
Signal Word Warning
Hazard Statements H351
Precautionary Statements P281
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xn: Harmful;
Risk Phrases R40
Safety Phrases 22-36
RIDADR NONH for all modes of transport
HS Code 2924299090

 Customs

HS Code 2924299090
Summary 2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Articles22

More Articles
Effect of glycyl-L-phenylalanine 2-naphthylamide on invertase endocytosed by rat liver.

Biochem. J. 225(3) , 645-8, (1985)

The release by glycyl-L-phenylalanine 2-naphthylamide (Gly-L-Phe-2-NNap) of endocytosed invertase associated with the MLP fraction (sum of the M, L and P fractions [de Duve, Pressman, Gianetto, Wattia...

Constitutive lysosome exocytosis releases ATP and engages P2Y receptors in human monocytes.

J. Cell Sci. 125(Pt 19) , 4567-75, (2012)

Elucidating mechanisms by which Ca(2+) signals are generated by monocytes is important for understanding monocyte function in health and disease. We have investigated mechanisms underlying Ca(2+) sign...

Calcium mobilization by nicotinic acid adenine dinucleotide phosphate (NAADP) in rat astrocytes.

Cell Calcium 39(2) , 143-53, (2006)

Nicotinic acid adenine dinucleotide phosphate (NAADP) has been shown to release intracellular Ca(2+) in several types of cells. We have used Ca(2+)-sensitive fluorescent dyes (Fura-2, Fluo-4) to measu...

 Synonyms

GLY-PHE β-NAPHTHYLAMIDE
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