(+)-syringaresinol

Modify Date: 2024-01-06 11:01:59

(+)-syringaresinol Structure
(+)-syringaresinol structure
Common Name (+)-syringaresinol
CAS Number 21453-69-0 Molecular Weight 418.437
Density 1.3±0.1 g/cm3 Boiling Point 594.7±50.0 °C at 760 mmHg
Molecular Formula C22H26O8 Melting Point N/A
MSDS N/A Flash Point 313.5±30.1 °C

 Use of (+)-syringaresinol


(+)-Syringaresinol, a lignan, is a NFAT transcription factor inhibitor, with an IC50 of 329.4 μM. (+)-Syringaresinol also can be used for the research of lymphocytic leukemia[1][2].

 Names

Name (+)-syringaresinol
Synonym More Synonyms

 (+)-syringaresinol Biological Activity

Description (+)-Syringaresinol, a lignan, is a NFAT transcription factor inhibitor, with an IC50 of 329.4 μM. (+)-Syringaresinol also can be used for the research of lymphocytic leukemia[1][2].
Related Catalog
Target

IC50: 329.4 μM (NFAT transcription factor)[1]

In Vitro (+)-Syringaresinol inhibits the growth of P-388 cells, with an ED50 0.41 μg/mL[1].
References

[1]. Cai XF, et, al. Inhibitory lignans against NFAT transcription factor from Acanthopanax koreanum. Arch Pharm Res. 2004 Jul;27(7):738-41.

[2]. Badawi MM, et, al. Plant anticancer agents XXVII: Antileukemic and cytotoxic constituents of Dirca occidentalis (Thymelaeaceae). J Pharm Sci. 1983 Nov;72(11):1285-7.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 594.7±50.0 °C at 760 mmHg
Molecular Formula C22H26O8
Molecular Weight 418.437
Flash Point 313.5±30.1 °C
Exact Mass 418.162781
PSA 95.84000
LogP 0.71
Vapour Pressure 0.0±1.7 mmHg at 25°C
Index of Refraction 1.578

 Synonyms

syringaresinol
(+)-(7S,7'S,8R,8'R)-4,4'-dihydroxy-3,3',5,5'-tetramethoxy-7,9':7',9-diepoxylignane
4,4'-(1S,3aR,4S,6aR)-Tetrahydro-1H,3H-furo[3,4-c]furan-1,4-diylbis(2,6-dimethoxyphenol)
Phenol, 4,4'-[(1S,3aR,4S,6aR)-tetrahydro-1H,3H-furo[3,4-c]furan-1,4-diyl]bis[2,6-dimethoxy-
(-) Syringaresinol
(+)-lirioresinol B
(+/-)-syringaresinol
4,4'-(tetrahydro-1H,3H-furo[3,4-c]furan-1,4-diyl)bis[2,6-dimethoxyphenyl]
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