WHI-P258
Modify Date: 2025-08-23 19:34:13
WHI-P258 structure
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Common Name | WHI-P258 | ||
|---|---|---|---|---|
| CAS Number | 21561-09-1 | Molecular Weight | 281.309 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 441.2±40.0 °C at 760 mmHg | |
| Molecular Formula | C16H15N3O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 220.6±27.3 °C | |
Use of WHI-P258WHI-P258, a quinazoline compound, binds to the active site of JAK3 with an estimated Ki of 72 µM. WHI-P258 does not inhibit JAK3 and does not affect the thrombin-induced aggregation of platelets even at 100 μM[1][2]. |
| Name | 6,7-dimethoxy-N-phenylquinazolin-4-amine |
|---|---|
| Synonym | More Synonyms |
| Description | WHI-P258, a quinazoline compound, binds to the active site of JAK3 with an estimated Ki of 72 µM. WHI-P258 does not inhibit JAK3 and does not affect the thrombin-induced aggregation of platelets even at 100 μM[1][2]. |
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| Related Catalog | |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 441.2±40.0 °C at 760 mmHg |
| Molecular Formula | C16H15N3O2 |
| Molecular Weight | 281.309 |
| Flash Point | 220.6±27.3 °C |
| Exact Mass | 281.116425 |
| PSA | 56.27000 |
| LogP | 2.87 |
| Vapour Pressure | 0.0±1.1 mmHg at 25°C |
| Index of Refraction | 1.663 |
| Storage condition | -20℃ |
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~99%
WHI-P258 CAS#:21561-09-1 |
| Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 21, # 5 p. 1371 - 1375 |
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~%
WHI-P258 CAS#:21561-09-1 |
| Literature: Bioorganic and Medicinal Chemistry, , vol. 4, # 8 p. 1203 - 1207 |
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~%
WHI-P258 CAS#:21561-09-1 |
| Literature: Bioorganic and Medicinal Chemistry, , vol. 4, # 8 p. 1203 - 1207 |
| Precursor 3 | |
|---|---|
| DownStream 0 | |
| 4-Anilino-6,7-dimethoxychinazolin |
| 6,7-dimethoxy-4-phenylaminoquinazoline |
| HMS1662N04 |
| 4-anilino-6,7-dimethoxyquinazoline |
| 4-quinazolinamine, 6,7-dimethoxy-N-phenyl- |
| 4-PHENYLAMINO-6,7-DIMETHOXYQUINAZOLINE |
| WHI-P258 |