PK68
Modify Date: 2025-08-25 18:56:43
PK68 structure
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Common Name | PK68 | ||
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| CAS Number | 2173556-69-7 | Molecular Weight | 424.52 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C22H24N4O3S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of PK68PK68 is a potent and selective type II inhibitor of receptor-interacting kinase 1 (RIPK1) with an IC50 of ~90 nM, displays inhibition of RIPK1-dependent necroptosis. PK68 powerfully ameliorates TNF-induced systemic inflammatory response syndrome, and with great potential for use in the treatment of inflammatory disorders and cancer metastasis[1]. |
| Name | PK68 |
|---|
| Description | PK68 is a potent and selective type II inhibitor of receptor-interacting kinase 1 (RIPK1) with an IC50 of ~90 nM, displays inhibition of RIPK1-dependent necroptosis. PK68 powerfully ameliorates TNF-induced systemic inflammatory response syndrome, and with great potential for use in the treatment of inflammatory disorders and cancer metastasis[1]. |
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| Related Catalog | |
| Target |
IC50: ~ 90 nM (RIPK1)[1] |
| References |
| Molecular Formula | C22H24N4O3S |
|---|---|
| Molecular Weight | 424.52 |