APN-C3-PEG4-azide

Modify Date: 2024-01-19 20:09:57

APN-C3-PEG4-azide Structure
APN-C3-PEG4-azide structure
Common Name APN-C3-PEG4-azide
CAS Number 2183440-32-4 Molecular Weight 500.55
Density N/A Boiling Point N/A
Molecular Formula C24H32N6O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of APN-C3-PEG4-azide


APN-C3-PEG4-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name APN-C3-PEG4-azide

 APN-C3-PEG4-azide Biological Activity

Description APN-C3-PEG4-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C24H32N6O6
Molecular Weight 500.55