Pomalidomide-PEG4-azide

Modify Date: 2025-08-26 16:43:48

Pomalidomide-PEG4-azide Structure
Pomalidomide-PEG4-azide structure
Common Name Pomalidomide-PEG4-azide
CAS Number 2271036-47-4 Molecular Weight 518.52
Density N/A Boiling Point N/A
Molecular Formula C23H30N6O8 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Pomalidomide-PEG4-azide


Pomalidomide-PEG4-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Pomalidomide-PEG4-azide

 Pomalidomide-PEG4-azide Biological Activity

Description Pomalidomide-PEG4-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C23H30N6O8
Molecular Weight 518.52
InChIKey SMHKJRVPSDESLS-UHFFFAOYSA-N
SMILES [N-]=[N+]=NCCOCCOCCOCCOCCNc1cccc2c1C(=O)N(C1CCC(=O)NC1=O)C2=O
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