Thalidomide-O-PEG4-azide

Modify Date: 2024-01-05 11:34:31

Thalidomide-O-PEG4-azide Structure
Thalidomide-O-PEG4-azide structure
Common Name Thalidomide-O-PEG4-azide
CAS Number 2380318-57-8 Molecular Weight 519.50
Density N/A Boiling Point N/A
Molecular Formula C23H29N5O9 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Thalidomide-O-PEG4-azide


Thalidomide-O-PEG4-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Thalidomide-O-PEG4-azide

 Thalidomide-O-PEG4-azide Biological Activity

Description Thalidomide-O-PEG4-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C23H29N5O9
Molecular Weight 519.50

 Safety Information

Hazard Codes Xi