Revexepride
Modify Date: 2024-01-17 15:41:08
Revexepride structure
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Common Name | Revexepride | ||
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| CAS Number | 219984-49-3 | Molecular Weight | 425.94900 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C21H32ClN3O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of RevexeprideRevexepride is a highly selective 5-HT4 receptor agonist, and a potential inducer of CYP3A4 enzyme, used for the treatment of gastroesophageal reflux disease. |
| Name | 4-amino-5-chloro-N-[[(3S,4S)-3-hydroxy-1-(3-methoxypropyl)piperidin-4-yl]methyl]-2,2-dimethyl-3H-1-benzofuran-7-carboxamide |
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| Synonym | More Synonyms |
| Description | Revexepride is a highly selective 5-HT4 receptor agonist, and a potential inducer of CYP3A4 enzyme, used for the treatment of gastroesophageal reflux disease. |
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| Related Catalog | |
| In Vitro | The human CYP isoenzymes are involved in the metabolism of revexepride, which is mainly metabolized in vitro in humans by CYP3A4 (99.9%) with a minor contribution of CYP2D6 (0.1%). Revexepride exhibits direct inhibition of human CYP3A4 in vitro with IC50 values of 16-49 μM[1]. |
| References |
| Molecular Formula | C21H32ClN3O4 |
|---|---|
| Molecular Weight | 425.94900 |
| Exact Mass | 425.20800 |
| PSA | 100.54000 |
| LogP | 3.17870 |
| Storage condition | 2-8℃ |
| Revexepride |
| UNII-8C63R2Y02M |