5,15-DIPHENYL-21H,23H-PORPHINE

Modify Date: 2024-01-02 09:31:48

5,15-DIPHENYL-21H,23H-PORPHINE Structure
5,15-DIPHENYL-21H,23H-PORPHINE structure
Common Name 5,15-DIPHENYL-21H,23H-PORPHINE
CAS Number 22112-89-6 Molecular Weight 462.544
Density 1.3±0.1 g/cm3 Boiling Point 912.3±65.0 °C at 760 mmHg
Molecular Formula C32H22N4 Melting Point N/A
MSDS Chinese USA Flash Point 401.3±27.2 °C

 Use of 5,15-DIPHENYL-21H,23H-PORPHINE


5,15-Diphenylporphyrin (5,15-DPP) is a selective STAT3-SH2 antagonist (IC50s of 0.28 µM and 10 µM for STAT3 and STAT1, respectively)[1].

 Names

Name 10,20-diphenyl-21,22-dihydroporphyrin
Synonym More Synonyms

 5,15-DIPHENYL-21H,23H-PORPHINE Biological Activity

Description 5,15-Diphenylporphyrin (5,15-DPP) is a selective STAT3-SH2 antagonist (IC50s of 0.28 µM and 10 µM for STAT3 and STAT1, respectively)[1].
Related Catalog
References

[1]. Uehara Y, et al. Novel high-throughput screening system for identifying STAT3-SH2 antagonists. Biochem Biophys Res Commun. 2009;380(3):627-631.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 912.3±65.0 °C at 760 mmHg
Molecular Formula C32H22N4
Molecular Weight 462.544
Flash Point 401.3±27.2 °C
Exact Mass 462.184448
PSA 56.30000
LogP 8.49
Vapour Pressure 0.0±0.3 mmHg at 25°C
Index of Refraction 1.705

 Safety Information

Hazard Codes Xi
RIDADR NONH for all modes of transport
HS Code 2933990090

 Synthetic Route

~90%

5,15-DIPHENYL-21H,23H-PORPHINE Structure

5,15-DIPHENYL-2...

CAS#:22112-89-6

Literature: Manka; Lawrence Tetrahedron Letters, 1989 , vol. 30, # 52 p. 7341 - 7344

~43%

5,15-DIPHENYL-21H,23H-PORPHINE Structure

5,15-DIPHENYL-2...

CAS#:22112-89-6

Literature: Vaz, Belen; Alvarez, Rosana; Nieto, Mar; Paniello, Antonio I; De Lera, Angel R Tetrahedron Letters, 2001 , vol. 42, # 42 p. 7409 - 7412

 Preparation


 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

5,15-Diphenyl-21H,23H-porphine,5,15-Diphenylporphyrin,5,15-diphenyl-Porphine
21H,23H-5,15-diphenylporphine
5,15-Diphenylporphyrin
21H,23H-Porphine, 5,15-diphenyl-
10,20-diphenylporphyrin
10,20-diphenylporphyrine
5,15-diphenyl-21H,23H-porphyrin
5,15-Diphenyl-21H,23H-porphine
5,15-diphenylphorphyrin
21H,23H-Porphine,5,15-diphenyl
5,15-diphenylporphine