2-Methylthio-AMP TEA salt
Modify Date: 2025-08-25 11:49:00
2-Methylthio-AMP TEA salt structure
|
Common Name | 2-Methylthio-AMP TEA salt | ||
|---|---|---|---|---|
| CAS Number | 22140-20-1 | Molecular Weight | 393.31300 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C11H16N5O7PS | Melting Point | N/A | |
| MSDS | USA | Flash Point | N/A | |
Use of 2-Methylthio-AMP TEA salt2-Methylthio-AMP (2-MeSAMP) is a selective and direct P2Y12 antagonist. 2-Methylthio-AMP is an inhibitor of ADP-dependent platelet aggregation[1][2][3]. |
| Name | 2-methylthioadenosine 5-monophosphate |
|---|---|
| Synonym | More Synonyms |
| Description | 2-Methylthio-AMP (2-MeSAMP) is a selective and direct P2Y12 antagonist. 2-Methylthio-AMP is an inhibitor of ADP-dependent platelet aggregation[1][2][3]. |
|---|---|
| Related Catalog | |
| Target |
P2Y12[1] |
| In Vitro | 2-Methylthio-AMP (2-MeSAMP) inhibits agonist-mediated αIIbβ3 activation in platelets[1]. 2-methylthio-AMP (50 μM; for 5 minutes) does not significantly inhibit thrombin, PAR1-AP, PAR4-AP, or ADP-mediated platelet Ca2+ mobilization. 2-methylthio-AMP fails to inhibit Ca2+ mobilization in P2Y12-deficient mouse platelets and does not raise cAMP or induce vasodilator-stimulated phosphoprotein phosphorylation in wild-type platelets[1]. |
| References |
| Molecular Formula | C11H16N5O7PS |
|---|---|
| Molecular Weight | 393.31300 |
| Exact Mass | 393.05100 |
| PSA | 221.18000 |
| 2-methylthioadenosine 5'-monophosphate triethylammonium salt hydrate |
| 2-MeSAMP,2-Methylthio-AMP hydrate triethylammonium salt |
| 2-Methylthio-AMP |
| 2-mesamp |
| 2,6,2',6'-TETRAMETHYLAZOBENZENE NN'-DIOXIDE---CRYSTALLINE |
| 2-methylthioadenosine-5'-monophosphate |