Jaspamycin
Modify Date: 2024-01-20 19:18:48
Jaspamycin structure
|
Common Name | Jaspamycin | ||
|---|---|---|---|---|
| CAS Number | 22242-96-2 | Molecular Weight | 292.25 | |
| Density | 1.91g/cm3 | Boiling Point | 724.3ºC at 760 mmHg | |
| Molecular Formula | C12H12N4O5 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 391.8ºC | |
Use of JaspamycinJaspamycin (7-CN-7-C-Ino) is a potent activator of PKA, binding to the R site (PKAR), with an EC50 of 6.5 nM and Kd of 8 nM in Trypanosoma brucei. Jaspamycin (7-CN-7-C-Ino) does not bind with purified human PKARIα. Anti-parasite activity[1]. |
| Name | 1,3-benzodioxol-2-one |
|---|---|
| Synonym | More Synonyms |
| Description | Jaspamycin (7-CN-7-C-Ino) is a potent activator of PKA, binding to the R site (PKAR), with an EC50 of 6.5 nM and Kd of 8 nM in Trypanosoma brucei. Jaspamycin (7-CN-7-C-Ino) does not bind with purified human PKARIα. Anti-parasite activity[1]. |
|---|---|
| Related Catalog | |
| Target |
Trypanosoma brucei PKAR(199-499):6.5 nM (EC50) Trypanosoma brucei PKA holoenzyme:8 nM (Kd) |
| References |
| Density | 1.91g/cm3 |
|---|---|
| Boiling Point | 724.3ºC at 760 mmHg |
| Molecular Formula | C12H12N4O5 |
| Molecular Weight | 292.25 |
| Flash Point | 391.8ºC |
| Exact Mass | 292.08100 |
| PSA | 144.39000 |
| Vapour Pressure | 5.1E-22mmHg at 25°C |
| Index of Refraction | 1.827 |
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