ATG7-IN-3

Modify Date: 2024-01-14 11:47:00

ATG7-IN-3 structure	Common Name	ATG7-IN-3
	CAS Number	2226229-76-9	Molecular Weight	376.41
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₁H₁₆N₆O₅S₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of ATG7-IN-3

ATG7-IN-3 (compound 18) is a potent ATG7 inhibitor, with an IC50 of 0.048 μM. ATG7-IN-3 inhibits autophagy. ATG7-IN-3 inhibits the formation of endogenous LC3B puncta in the neuroglioma cell line H4[1].

Name	ATG7-IN-3

Description	ATG7-IN-3 (compound 18) is a potent ATG7 inhibitor, with an IC50 of 0.048 μM. ATG7-IN-3 inhibits autophagy. ATG7-IN-3 inhibits the formation of endogenous LC3B puncta in the neuroglioma cell line H4[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Autophagy >> Autophagy
Target	IC50: 0.048 ± 0.022 μM (ATG7), 0.280 ± 0.051 μM (Thioester), 0.938 ± 0.231 μM (LC3B)[1]
References	[1]. Huang SC, et al. Discovery and optimization of pyrazolopyrimidine sulfamates as ATG7 inhibitors. Bioorg Med Chem. 2020 Oct 1;28(19):115681.

Molecular Formula	C₁₁H₁₆N₆O₅S₂
Molecular Weight	376.41