Dynapyrazole-A

Modify Date: 2024-02-15 12:08:50

Dynapyrazole-A structure	Common Name	Dynapyrazole-A
	CAS Number	2226517-75-3	Molecular Weight	486.7
	Density	1.9±0.1 g/cm3	Boiling Point	551.3±50.0 °C at 760 mmHg
	Molecular Formula	C₂₀H₁₂ClIN₄O	Melting Point	N/A
	MSDS	N/A	Flash Point	287.2±30.1 °C

Use of Dynapyrazole-A

Dynapyrazole A is a specific inhibitor of microtubule dynamin that specifically inhibits the ATPase activity of microtubule-stimulated dynamin without blocking microtubule-independent basal activity[1].

Name	Dynapyrazole A
Synonym	More Synonyms

Description	Dynapyrazole A is a specific inhibitor of microtubule dynamin that specifically inhibits the ATPase activity of microtubule-stimulated dynamin without blocking microtubule-independent basal activity[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Cytoskeleton >> Dynamin
In Vitro	Dynapyrazole A (1- 3 μg/mL, 14 h) 在感染了 RVA-NMTL 病毒的 MA-104 细胞中，可以以剂量依赖的方式降低病毒滴度，EC 50 值为 0.73 μg/mL[1]。
References	[1]. Zhaoyang Jing, et al. Rotavirus Viroplasm Biogenesis Involves Microtubule-Based Dynein Transport Mediated by an Interaction between NSP2 and Dynein Intermediate Chain. J Virol. 2021 Oct 13;95(21):e0124621.

Density	1.9±0.1 g/cm3
Boiling Point	551.3±50.0 °C at 760 mmHg
Molecular Formula	C₂₀H₁₂ClIN₄O
Molecular Weight	486.7
Flash Point	287.2±30.1 °C
Exact Mass	485.974426
LogP	5.45
Vapour Pressure	0.0±1.5 mmHg at 25°C
Index of Refraction	1.821

2-[1-(4-Chlorophenyl)cyclopropyl]-4,5-dihydro-7-iodo-5-oxopyrazolo[1,5-a]quinazoline-3-carbonitrile

2-[1-(4-Chlorophenyl)cyclopropyl]-7-iodo-5-oxo-4,5-dihydropyrazolo[1,5-a]quinazoline-3-carbonitrile

2-[1-(4-Chloro-phenyl)-cyclopropyl]-7-iodo-5-oxo-4,5-dihydro-pyrazolo[1,5-a]quinazoline-3-carbonitrile

Pyrazolo[1,5-a]quinazoline-3-carbonitrile, 2-[1-(4-chlorophenyl)cyclopropyl]-4,5-dihydro-7-iodo-5-oxo-

Dynapyrazole-A

Dynapyrazole-A

Use of Dynapyrazole-A

Names

Dynapyrazole-A Biological Activity

Chemical & Physical Properties

Synonyms