Noladin ether

Modify Date: 2024-01-04 20:37:49

Noladin ether Structure
Noladin ether structure
Common Name Noladin ether
CAS Number 222723-55-9 Molecular Weight 364.562
Density 0.9±0.1 g/cm3 Boiling Point 488.9±45.0 °C at 760 mmHg
Molecular Formula C23H40O3 Melting Point N/A
MSDS USA Flash Point 249.5±28.7 °C
Symbol GHS02 GHS07
GHS02, GHS07
Signal Word Danger

 Use of Noladin ether


Noladin ether is a potent and selective agonist of cannabinoid CB1 receptor, with a Ki of 21.2 nM. Noladin ether can cause hypothermia, intestinal immobility, and mild antinociception[1].

 Names

Name 2-O-arachidonylglycerol
Synonym More Synonyms

 Noladin ether Biological Activity

Description Noladin ether is a potent and selective agonist of cannabinoid CB1 receptor, with a Ki of 21.2 nM. Noladin ether can cause hypothermia, intestinal immobility, and mild antinociception[1].
Related Catalog
Target

CB1:21.2 nM (Ki)

CB2:>3 mM (Ki)

References

[1]. Hanus L, et, al. 2-arachidonyl glyceryl ether, an endogenous agonist of the cannabinoid CB1 receptor. Proc Natl Acad Sci U S A. 2001 Mar 27;98(7):3662-5.

 Chemical & Physical Properties

Density 0.9±0.1 g/cm3
Boiling Point 488.9±45.0 °C at 760 mmHg
Molecular Formula C23H40O3
Molecular Weight 364.562
Flash Point 249.5±28.7 °C
Exact Mass 364.297760
PSA 49.69000
LogP 6.69
Vapour Pressure 0.0±2.8 mmHg at 25°C
Index of Refraction 1.503

 Safety Information

Symbol GHS02 GHS07
GHS02, GHS07
Signal Word Danger
Hazard Statements H225-H319
Precautionary Statements P210-P280-P305 + P351 + P338-P337 + P313-P403 + P235
RIDADR UN1170 - class 3 - PG 2 - Ethanol, solution

 Synonyms

2-[(5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoxy]propane-1,3-diol
2-AG ether
2-Arachidonyl Glycerol ether
2-arachidonyl glyceryl ether
1,3-Propanediol, 2-[(5Z,8Z,11Z,14Z)-5,8,11,14-eicosatetraen-1-yloxy]-
2-[(5Z,8Z,11Z,14Z)-5,8,11,14-Icosatetraen-1-yloxy]-1,3-propanediol
2-[(5Z,8Z,11Z,14Z)-Icosa-5,8,11,14-tetraen-1-yloxy]propane-1,3-diol
2-AG ether HU 310
Noladin
noladin ether
1,3-Propanediol, 2-[(5Z,8Z,11Z,14Z)-5,8,11,14-eicosatetraenyloxy]-
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