GSK-3 inhibitor 3
Modify Date: 2025-08-27 07:53:44
GSK-3 inhibitor 3 structure
|
Common Name | GSK-3 inhibitor 3 | ||
|---|---|---|---|---|
| CAS Number | 2227279-84-5 | Molecular Weight | 410.40 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C23H15FN6O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of GSK-3 inhibitor 3GSK-3 inhibitor 3 is a selective, orally active and brain-penetrant inhibitor of GSK-3, with IC50s of 0.35 nM and 0.25 nM for GSK-3α and GSK-3β, respectively. GSK-3 inhibitor 3 lowers levels of tau protein phosphorylation at S396 in a triple-transgenic mouse Alzheimer’s disease model, with IC50 of 10 nM. GSK-3 inhibitor 3 can be used for neurological disease research[1]. |
| Name | GSK-3 inhibitor 3 |
|---|
| Description | GSK-3 inhibitor 3 is a selective, orally active and brain-penetrant inhibitor of GSK-3, with IC50s of 0.35 nM and 0.25 nM for GSK-3α and GSK-3β, respectively. GSK-3 inhibitor 3 lowers levels of tau protein phosphorylation at S396 in a triple-transgenic mouse Alzheimer’s disease model, with IC50 of 10 nM. GSK-3 inhibitor 3 can be used for neurological disease research[1]. |
|---|---|
| Related Catalog | |
| Target |
GSK-3α:0.35 nM (IC50) GSK-3β:0.25 nM (IC50) CDK2:0.22 μM (IC50) CDK5:1.3 μM (IC50) |
| References |
| Molecular Formula | C23H15FN6O |
|---|---|
| Molecular Weight | 410.40 |