Methyl 3-amino-2-thiophenecarboxylate

Methyl 3-amino-2-thiophenecarboxylate Structure
Methyl 3-amino-2-thiophenecarboxylate structure
Common Name Methyl 3-amino-2-thiophenecarboxylate
CAS Number 22288-78-4 Molecular Weight 157.190
Density 1.3±0.1 g/cm3 Boiling Point 334.6±0.0 °C at 760 mmHg
Molecular Formula C6H7NO2S Melting Point 62-64 °C(lit.)
MSDS Chinese USA Flash Point 138.1±22.3 °C
Symbol GHS07
GHS07
Signal Word Warning

A short synthesis of quinazolinocarboline alkaloids rutaecarpine, hortiacine, euxylophoricine A and euxylophoricine D from methyl N-(4-chloro-5H-1, 2, 3-dithiazol-5-ylidene) anthranilates. Mohanta PK and Kim K.

Tetrahedron Lett. 43(22) , 3993-96, (2002)

Synthesis and Properties of Some New 1, 4-Dihydrothieno [3, 2-e][1, 2, 4] triazepin-5-ones. Sabri SS, et al.

Z. Naturforsch. B 61(1) , 65, (2006)

The discovery and optimization of pyrimidinone-containing MCH R1 antagonists.

Bioorg. Med. Chem. Lett. 16(18) , 4723-27, (2006)

Optimization of a series of constrained melanin-concentrating hormone receptor 1 (MCH R1) antagonists has provided compounds with potent and selective MCH R1 activity. Details of the optimization process are provided and the use of one of the compounds in an ...

p38 kinase inhibitors for the treatment of arthritis and osteoporosis: thienyl, furyl, and pyrrolyl ureas.

Bioorg. Med. Chem. Lett. 11(1) , 9-12, (2001)

Inhibitors of the MAP kinase p38 are potentially useful for the treatment for osteoporosis, arthritis, and other inflammatory diseases. A series of thienyl, furyl, and pyrrolyl ureas has been identified as potent p38 inhibitors, displaying in vitro activity i...