DBCO-PEG1-acid

Modify Date: 2025-08-26 19:47:32

DBCO-PEG1-acid Structure
DBCO-PEG1-acid structure
Common Name DBCO-PEG1-acid
CAS Number 2228857-38-1 Molecular Weight 420.46
Density N/A Boiling Point N/A
Molecular Formula C24H24N2O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of DBCO-PEG1-acid


DBCO-PEG1-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name DBCO-PEG1-acid
Synonym More Synonyms

 DBCO-PEG1-acid Biological Activity

Description DBCO-PEG1-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C24H24N2O5
Molecular Weight 420.46

 Synonyms

MFCD31654043
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