Betamethasone 17-benzoate

Modify Date: 2024-01-02 08:43:32

Betamethasone 17-benzoate Structure
Betamethasone 17-benzoate structure
Common Name Betamethasone 17-benzoate
CAS Number 22298-29-9 Molecular Weight 496.56700
Density N/A Boiling Point N/A
Molecular Formula C29H33FO6 Melting Point 225-228°
MSDS N/A Flash Point N/A

 Use of Betamethasone 17-benzoate


Betamethasone 17-benzoate is a representative steroid, which can be used in the treatment of recurrent aphothous ulcers (RAU).

 Names

Name [(8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11-hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] benzoate
Synonym More Synonyms

 Betamethasone 17-benzoate Biological Activity

Description Betamethasone 17-benzoate is a representative steroid, which can be used in the treatment of recurrent aphothous ulcers (RAU).
Related Catalog
In Vitro Betamethasone 17-benzoate is the topical steroid[1]. Betamethasone 17-benzoate is a local corticosteroid[2]. A double-blind study of the effectiveness of Betamethasone 17-benzoate in the treatment of recurrent aphothous ulcers (RAU) is concucted. Betamethasone 17-benzoate is found to be effective in reducing symptoms and shortening healing time but not in preventing recurrences[3].
References

[1]. Barry BW, et al. Optimization of bioavailability of topical steroids: penetration enhancers under occlusion. J Invest Dermatol. 1984 Jan;82(1):49-52.

[2]. ZFA (Stuttgart). 1978 Jul 10;54(19):1031-2.

[3]. Merchant HW, et al. Betamethasone-17-benzoate in the treatment of recurrent aphthous ulcers. Oral Surg Oral Med Oral Pathol. 1978 Jun;45(6):870-5.

 Chemical & Physical Properties

Melting Point 225-228°
Molecular Formula C29H33FO6
Molecular Weight 496.56700
Exact Mass 496.22600
PSA 100.90000
LogP 3.76040
Vapour Pressure 2.62E-17mmHg at 25°C

 Safety Information

RIDADR UN 2811 6.1 / PGII

 Synonyms

MS 1112
BETAMETHASONE BENZOATE
Uticort (TN)
Betamethasone benzoate
Betamethasone 17-benzoate
Benisone
EINECS 244-897-9
W 5975