TT-10

Modify Date: 2025-08-21 20:53:46

TT-10 Structure
TT-10 structure
 Common Name TT-10
CAS Number 2230640-94-3 Molecular Weight 283.339
Density N/A Boiling Point N/A
Molecular Formula C11H10FN3OS2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of TT-10


TT-10 (YAP-TEAD activator TT-10) is a small molecule activator that activates pro-proliferative YES-associated protein (YAP) and transcriptional enhancer factor domain (TEAD) activities in cardiomyocytes; promoted cardiomyocyte proliferation and simultaneously exerted antioxidant and antiapoptotic effects in vitro via nuclear translocation of YAP, activates YAP-TEADs activity and the Wnt/β-Catenin signaling pathway; ameliorates cardiac dysfunction, decreases ROS and DNA aamage and apoptosis after myocardial infarction (MI) in mice.

 Names

Name TT-10

 TT-10 Biological Activity

Description TT-10 (YAP-TEAD activator TT-10) is a small molecule activator that activates pro-proliferative YES-associated protein (YAP) and transcriptional enhancer factor domain (TEAD) activities in cardiomyocytes; promoted cardiomyocyte proliferation and simultaneously exerted antioxidant and antiapoptotic effects in vitro via nuclear translocation of YAP, activates YAP-TEADs activity and the Wnt/β-Catenin signaling pathway; ameliorates cardiac dysfunction, decreases ROS and DNA aamage and apoptosis after myocardial infarction (MI) in mice.
References References 1. Hara H, et al. JACC Basic Transl Sci. 2018 Nov 12;3(5):639-653. View Related Products by Target Yes-associated Protein (YAP)

 Chemical & Physical Properties

Molecular Formula C11H10FN3OS2
Molecular Weight 283.339
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Chemsrc provides TT-10(CAS#:2230640-94-3) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of TT-10 are included as well.>> amp version: TT-10

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