ACP-5862
Modify Date: 2024-01-02 21:32:44
ACP-5862 structure
|
Common Name | ACP-5862 | ||
|---|---|---|---|---|
| CAS Number | 2230757-47-6 | Molecular Weight | 481.51 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C26H23N7O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of ACP-5862ACP-5862 is a major active, circulating, pyrrolidine ring-opened metabolite of Acalabrutinib with an IC50 of 5.0 nM for Bruton tyrosine kinase (BTK)[1]. Acalabrutinib is an orally active, irreversible, and highly selective BTK inhibitor, with an IC50 of 3 nM and EC50 of 8 nM[2]. |
| Name | ACP-5862 |
|---|
| Description | ACP-5862 is a major active, circulating, pyrrolidine ring-opened metabolite of Acalabrutinib with an IC50 of 5.0 nM for Bruton tyrosine kinase (BTK)[1]. Acalabrutinib is an orally active, irreversible, and highly selective BTK inhibitor, with an IC50 of 3 nM and EC50 of 8 nM[2]. |
|---|---|
| Related Catalog | |
| Target |
IC50: 5.0 nM (BTK)[1] |
| References |
| Molecular Formula | C26H23N7O3 |
|---|---|
| Molecular Weight | 481.51 |