JT002
Modify Date: 2025-08-25 16:08:48
JT002 structure
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Common Name | JT002 | ||
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| CAS Number | 2238820-43-2 | Molecular Weight | 432.49 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C20H24N4O5S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of JT002JT002 is an orally active inhibitor of the NLRP3 inflammasome. JT002 reduces NLRP3-dependent proinflammatory cytokine (such as IL-1β, IL-1α, IL-18) production and pyroptosis. JT002 blocks NLRP3 inflammasome complex formation. JT002 reduces airway hyperresponsiveness and airway neutrophilia in mice[1]. |
| Name | JT002 |
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| Description | JT002 is an orally active inhibitor of the NLRP3 inflammasome. JT002 reduces NLRP3-dependent proinflammatory cytokine (such as IL-1β, IL-1α, IL-18) production and pyroptosis. JT002 blocks NLRP3 inflammasome complex formation. JT002 reduces airway hyperresponsiveness and airway neutrophilia in mice[1]. |
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| References |
| Molecular Formula | C20H24N4O5S |
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| Molecular Weight | 432.49 |
| InChIKey | CNMWUSIUEKOFMW-AWEZNQCLSA-N |
| SMILES | COC1COc2c(S(=O)(=O)NC(=O)Nc3c4c(cc5c3CCC5)CCC4)cnn2C1 |