JT002

Modify Date: 2025-08-25 16:08:48

JT002 Structure
JT002 structure
Common Name JT002
CAS Number 2238820-43-2 Molecular Weight 432.49
Density N/A Boiling Point N/A
Molecular Formula C20H24N4O5S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of JT002


JT002 is an orally active inhibitor of the NLRP3 inflammasome. JT002 reduces NLRP3-dependent proinflammatory cytokine (such as IL-1β, IL-1α, IL-18) production and pyroptosis. JT002 blocks NLRP3 inflammasome complex formation. JT002 reduces airway hyperresponsiveness and airway neutrophilia in mice[1].

 Names

Name JT002

 JT002 Biological Activity

Description JT002 is an orally active inhibitor of the NLRP3 inflammasome. JT002 reduces NLRP3-dependent proinflammatory cytokine (such as IL-1β, IL-1α, IL-18) production and pyroptosis. JT002 blocks NLRP3 inflammasome complex formation. JT002 reduces airway hyperresponsiveness and airway neutrophilia in mice[1].
Related Catalog
References

[1]. Ambrus-Aikelin G, et al. JT002, a small molecule inhibitor of the NLRP3 inflammasome for the treatment of autoinflammatory disorders. Sci Rep. 2023 Aug 19;13(1):13524.  

 Chemical & Physical Properties

Molecular Formula C20H24N4O5S
Molecular Weight 432.49
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