methyl (4aS,6aR,6aS,6bR,10R,11R,12aR,14bR)-10,11-dihydroxy-2,2,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylate
Modify Date: 2024-01-07 18:07:24
methyl (4aS,6aR,6aS,6bR,10R,11R,12aR,14bR)-10,11-dihydroxy-2,2,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylate structure
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Common Name | methyl (4aS,6aR,6aS,6bR,10R,11R,12aR,14bR)-10,11-dihydroxy-2,2,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylate | ||
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| CAS Number | 22425-82-7 | Molecular Weight | 486.72600 | |
| Density | 1.11g/cm3 | Boiling Point | 541.9ºC at 760mmHg | |
| Molecular Formula | C31H50O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 163.1ºC | |
Use of methyl (4aS,6aR,6aS,6bR,10R,11R,12aR,14bR)-10,11-dihydroxy-2,2,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylateMethyl maslinate is a β-adrenergic antagonist. Methyl maslinate is a potent cardiotonic and antidysrhythmic agent. Methyl maslinate has the potential for hypertension research[1]. |
| Name | methyl (4aS,6aR,6aS,6bR,10R,11R,12aR,14bR)-10,11-dihydroxy-2,2,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylate |
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| Synonym | More Synonyms |
| Description | Methyl maslinate is a β-adrenergic antagonist. Methyl maslinate is a potent cardiotonic and antidysrhythmic agent. Methyl maslinate has the potential for hypertension research[1]. |
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| Related Catalog | |
| In Vivo | Methyl maslinate (MM) (20-60 mg/kg; i.p.) shows significant, dose-dependent vasodepressor effect and sinus bradycardia, lasting more than 60 minutes with a maximum at 20 minutes, and shows potent hymodynamic effect[1]. Methyl maslinate (40 mg/kg) shows antidysrhythmic activity on ischemia-reperfusion dysrhythmia[1]. Animal Model: Wistar male rats (300-320 g)[1] Dosage: 20-60 mg/kg Administration: Intraperitoneal injection; once Result: Showed significant, dose-response vasodepressor effect and sinus bradicardia. Antagonized β-Adrenergic. Showed antidysrhythmic activity. |
| References |
| Density | 1.11g/cm3 |
|---|---|
| Boiling Point | 541.9ºC at 760mmHg |
| Molecular Formula | C31H50O4 |
| Molecular Weight | 486.72600 |
| Flash Point | 163.1ºC |
| Exact Mass | 486.37100 |
| PSA | 66.76000 |
| LogP | 6.29280 |
| Vapour Pressure | 5.29E-14mmHg at 25°C |
| Index of Refraction | 1.552 |
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| Methyl maslinate |
| Maslinic acid methyl ester |
| 2alpha,3beta-Dihydroxyolean-12-en-28-oic acid methyl ester |