Erythrodiol
Erythrodiol structure
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Common Name | Erythrodiol | ||
|---|---|---|---|---|
| CAS Number | 545-48-2 | Molecular Weight | 442.717 | |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 520.5±50.0 °C at 760 mmHg | |
| Molecular Formula | C30H50O2 | Melting Point | 230-231ºC(lit.) | |
| MSDS | Chinese USA | Flash Point | 209.9±24.7 °C | |
Use of ErythrodiolErythrodiol is an olive oil component. Erythrodiol promotes Cholesterol efflux (ChE) by selectively inhibiting the degradation of ABCA1 protein. Erythrodiol is a good candidate to be further explored for therapeutic or preventive application in the context of atherosclerosis[1]. |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | erythrodiol |
|---|---|
| Synonym | More Synonyms |
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | Erythrodiol is an olive oil component. Erythrodiol promotes Cholesterol efflux (ChE) by selectively inhibiting the degradation of ABCA1 protein. Erythrodiol is a good candidate to be further explored for therapeutic or preventive application in the context of atherosclerosis[1]. |
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| Related Catalog | |
| In Vitro | Erythrodiol (1-15 μM; 24 hours) enhances ABCA1 protein level in a concentration-dependent manner, and reachs significance at 10 and 15 μM[1]. Western Blot Analysis[1] Cell Line: THP-1 macrophage cells Concentration: 1 μM, 2.5 μM, 5 μM, 10 μM, and 15 μM Incubation Time: 24 hours Result: Increased ABCA1 protein expression. |
| References |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 520.5±50.0 °C at 760 mmHg |
| Melting Point | 230-231ºC(lit.) |
| Molecular Formula | C30H50O2 |
| Molecular Weight | 442.717 |
| Flash Point | 209.9±24.7 °C |
| Exact Mass | 442.381073 |
| PSA | 40.46000 |
| LogP | 9.18 |
| Vapour Pressure | 0.0±3.1 mmHg at 25°C |
| Index of Refraction | 1.551 |
| InChIKey | PSZDOEIIIJFCFE-OSQDELBUSA-N |
| SMILES | CC1(C)CCC2(CO)CCC3(C)C(=CCC4C5(C)CCC(O)C(C)(C)C5CCC43C)C2C1 |
This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.
This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Hazard Codes | Xi |
| Risk Phrases | R22 |
| Safety Phrases | 2-45 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 6 | |
|---|---|
| DownStream 2 | |
CAS#:508-02-1
CAS#:107387-66-6
CAS#:118800-83-2
CAS#:6153-31-7
CAS#:152487-59-7
CAS#:77-52-1
CAS#:559-70-6
CAS#:17990-42-0This table lists relevant public references with title, journal and publication metadata for this compound.
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Potential vasorelaxant effects of oleanolic acid and erythrodiol, two triterpenoids contained in 'orujo' olive oil, on rat aorta.
Br. J. Nutr. 92(4) , 635-42, (2004) 'Orujo' olive oil is obtained by chemical processes from the waste resulting from the mechanical extraction of virgin olive oil. The aim of the present study was to evaluate a new pharmacological prop... |
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Changes of the wax contents in mixtures of olive oils as determined by gas chromatography with a flame ionization detector.
J. AOAC Int. 95(6) , 1720-4, (2012) Mixing of refined olive-pomace oil with virgin olive oil is a fraud that has been tried often. Normally, the tests that detected the fraud were determinations of wax esters, erythrodiol+uvaol, and sti... |
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Modulation of cytokine secretion by pentacyclic triterpenes from olive pomace oil in human mononuclear cells.
Cytokine 36(5-6) , 211-7, (2006) Olive pomace oil, also known as "orujo" olive oil, is a blend of refined-pomace oil and virgin olive oil, fit for human consumption. Maslinic acid, oleanolic acid, erythrodiol, and uvaol are pentacycl... |
This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| HOMOOLESTRANOL |
| olean-12-ene-3,28-diol |
| MFCD00017294 |
| (3S,4aR,6aR,6bS,8aS,12aS,14aR,14bR)-8a-(Hydroxyméthyl)-4,4,6a,6b,11,11,14b-heptaméthyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydro-3-picénol |
| Erythrodiol |
| (3S,4aR,6aR,6bS,8aS,12aS,14aR,14bR)-8a-(Hydroxymethyl)-4,4,6a,6b,11,11,14b-heptamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydro-3-picenol |
| (3β)-Olean-12-ene-3,28-diol |
| EINECS 208-890-4 |
| Olean-12-ene-3β,28-diol |
| 12-OLEANENE-3,28-DIOL |
| (3β)-Olean-12-ène-3,28-diol |
| ERYTHODIOL |
| Oleanolic alcohol |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the polar surface area (PSA) of erythrodiol? |
| A: Polar surface area (PSA) of erythrodiol is 40.46000. |
| Q: What is the English name of erythrodiol? |
| A: The English name of erythrodiol is erythrodiol. |
| Q: What are the uses of erythrodiol? |
| A: Main uses of erythrodiol: Erythrodiol is an olive oil component. Erythrodiol promotes Cholesterol efflux (ChE) by selectively inhibiting the degradation of ABCA1 protein. Erythrodiol is a good candidate to be further explored for therapeutic or preventive application in the context of atherosclerosis[1]. |
| Q: What is the molecular formula of erythrodiol? |
| A: Molecular formula of erythrodiol is C30H50O2. |
| Q: What are the downstream products of erythrodiol? |
| A: Related downstream products(CAS) of erythrodiol: 559-70-6;17990-42-0. |
| Q: What is the melting point of erythrodiol? |
| A: Melting point of erythrodiol is 230-231ºC(lit.). |
| Q: What is the safety information for erythrodiol? |
| A: Safety information for erythrodiol: 2-45. |
| Q: What are the upstream materials of erythrodiol? |
| A: Related upstream materials(CAS) of erythrodiol: 508-02-1;107387-66-6;118800-83-2;6153-31-7;152487-59-7;77-52-1. |
| Q: What is the SMILES notation of erythrodiol? |
| A: SMILES notation of erythrodiol is CC1(C)CCC2(CO)CCC3(C)C(=CCC4C5(C)CCC(O)C(C)(C)C5CCC43C)C2C1. |
| Q: What is the InChIKey of erythrodiol? |
| A: InChIKey of erythrodiol is PSZDOEIIIJFCFE-OSQDELBUSA-N. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| BioBioPha |
| Dayang Chem (Hangzhou) Co., Ltd. |