Tubulin inhibitor 35
Modify Date: 2024-01-23 16:50:49
Tubulin inhibitor 35 structure
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Common Name | Tubulin inhibitor 35 | ||
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| CAS Number | 2247047-77-2 | Molecular Weight | 331.41 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C21H21N3O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Tubulin inhibitor 35Tubulin inhibitor 35 (compound 6b) is a dual inhibitor of topoisomerase I (IC50=~50 μM) and tubulin polymerization (IC50=5.69 μM). Tubulin inhibitor 35 inhibits migration and invasion of MGC-803 and RKO cell lines，and induces apoptosis via arresting cell cycle at G2/M phase. Tubulin inhibitor 35 exhibis potent efficacy in gastrointestinal tumor inhibiton (inhibits MGC-803 (IC50=0.09 μM) and RKO (IC50=0.2 μM) cell lines)[1]. |
| Name | Tubulin inhibitor 35 |
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| Description | Tubulin inhibitor 35 (compound 6b) is a dual inhibitor of topoisomerase I (IC50=~50 μM) and tubulin polymerization (IC50=5.69 μM). Tubulin inhibitor 35 inhibits migration and invasion of MGC-803 and RKO cell lines，and induces apoptosis via arresting cell cycle at G2/M phase. Tubulin inhibitor 35 exhibis potent efficacy in gastrointestinal tumor inhibiton (inhibits MGC-803 (IC50=0.09 μM) and RKO (IC50=0.2 μM) cell lines)[1]. |
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| References |
| Molecular Formula | C21H21N3O |
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| Molecular Weight | 331.41 |