KRAS G12C inhibitor 47

Modify Date: 2025-08-23 01:23:44

KRAS G12C inhibitor 47 structure	Common Name	KRAS G12C inhibitor 47
	CAS Number	2253119-24-1	Molecular Weight	547.02
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₃₀H₂₈ClFN₄O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of KRAS G12C inhibitor 47

KRAS G12C inhibitor 47 (compound 8-1-1) is a potent KRAS G12C inhibitor with an IC50 of 0.172 µM. KRAS G12C inhibitor 47 shows p-ERK inhibition activities with IC50s of 0.046, 69.8 µM in MIA PaCA-2, A549 cells, respectively. KRAS G12C inhibitor 47 has the potential for the research of pancreatic, colorectal, and lung cancers[1].

Name	KRAS G12C inhibitor 47

Description	KRAS G12C inhibitor 47 (compound 8-1-1) is a potent KRAS G12C inhibitor with an IC50 of 0.172 µM. KRAS G12C inhibitor 47 shows p-ERK inhibition activities with IC50s of 0.046, 69.8 µM in MIA PaCA-2, A549 cells, respectively. KRAS G12C inhibitor 47 has the potential for the research of pancreatic, colorectal, and lung cancers[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> GPCR/G Protein >> Ras
Target	KRas G12C:0.172 μM (IC50)
References	[1]. Brian alan, et al. KRAS g12c inhibitors and methods of using the same. WO2018119183 A2

Molecular Formula	C₃₀H₂₈ClFN₄O₃
Molecular Weight	547.02

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KRAS G12C inhibitor 47

Use of KRAS G12C inhibitor 47

Names

KRAS G12C inhibitor 47 Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.