SJFα

Modify Date: 2024-10-11 18:55:00

SJFα structure	Common Name	SJFα
	CAS Number	2254609-27-1	Molecular Weight	1120.27
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₅₉H₆₇F₂N₇O₁₁S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of SJFα

SJFα is a 13-atom linker PROTAC. SJFα degrades p38α with a DC50 of 7.16 nM, but is far less effective at degrading p38δ (DC50=299 nM) and does not degrade the other p38 isoforms (β and γ) at concentrations up to 2.5 µM[1].

Name	SJFα

Description	SJFα is a 13-atom linker PROTAC. SJFα degrades p38α with a DC50 of 7.16 nM, but is far less effective at degrading p38δ (DC50=299 nM) and does not degrade the other p38 isoforms (β and γ) at concentrations up to 2.5 µM[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> MAPK/ERK Pathway >> p38 MAPK Signaling Pathways >> PROTAC >> PROTAC
Target	p38α:7.16 nM (DC50) p38δ:299 nM (DC50) PROTAC
References	[1]. Smith BE, et al. Differential PROTAC substrate specificity dictated by orientation of recruited E3 ligase. Nat Commun. 2019 Jan 10;10(1):131.

Molecular Formula	C₅₉H₆₇F₂N₇O₁₁S
Molecular Weight	1120.27

Hazard Codes	Xi

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: SJFα
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Get all suppliers and price by the below link:

SJFα suppliers

SJFα price

SJFα

Use of SJFα

Names

SJFα Biological Activity

Chemical & Physical Properties

Safety Information

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.