DBCO-(PEG2-VC-PAB-MMAE)2

Modify Date: 2024-01-04 17:20:56

DBCO-(PEG2-VC-PAB-MMAE)2 Structure
DBCO-(PEG2-VC-PAB-MMAE)2 structure
Common Name DBCO-(PEG2-VC-PAB-MMAE)2
CAS Number 2259318-55-1 Molecular Weight 2835.50
Density N/A Boiling Point N/A
Molecular Formula C149H224N22O32 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of DBCO-(PEG2-VC-PAB-MMAE)2


DBCO-(PEG2-VC-PAB-MMAE)2 is made by MMAE conjugated to the cleavable DBCO-(PEG2-VC-PAB)2 linker. Monomethyl auristatin E (MMAE), a potent tubulin inhibitor, is a toxin payload in antibody drug conjugate[1].

 Names

Name DBCO-(PEG2-VC-PAB-MMAE)2

 DBCO-(PEG2-VC-PAB-MMAE)2 Biological Activity

Description DBCO-(PEG2-VC-PAB-MMAE)2 is made by MMAE conjugated to the cleavable DBCO-(PEG2-VC-PAB)2 linker. Monomethyl auristatin E (MMAE), a potent tubulin inhibitor, is a toxin payload in antibody drug conjugate[1].
Related Catalog
Target

Auristatin

References

[1]. Brian Lannutti, et al. Ror1 antibody immunoconjugates. WO2018237335A1.

 Chemical & Physical Properties

Molecular Formula C149H224N22O32
Molecular Weight 2835.50