TCO-PEG4-VC-PAB-MMAE
Modify Date: 2025-09-10 19:49:59
TCO-PEG4-VC-PAB-MMAE structure
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Common Name | TCO-PEG4-VC-PAB-MMAE | ||
|---|---|---|---|---|
| CAS Number | 2758671-45-1 | Molecular Weight | 1522.91 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C78H127N11O19 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of TCO-PEG4-VC-PAB-MMAETCO-PEG4-VC-PAB-MMAE is a drug-linker conjugate for ADC. TCO-PEG4-VC-PAB-MMAE contains a cleavable ADC linker (TCO-PEG4-VC-PA) and a potent tubulin inhibitor MMAE (HY-15162)[1]. |
| Name | TCO-PEG4-VC-PAB-MMAE |
|---|
| Description | TCO-PEG4-VC-PAB-MMAE is a drug-linker conjugate for ADC. TCO-PEG4-VC-PAB-MMAE contains a cleavable ADC linker (TCO-PEG4-VC-PA) and a potent tubulin inhibitor MMAE (HY-15162)[1]. |
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| Related Catalog | |
| In Vitro | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. |
| References |
[1]. Yang Yi, et al. Preparation of site-specific antibody conjugates. Patent WO2022037665. |
| Molecular Formula | C78H127N11O19 |
|---|---|
| Molecular Weight | 1522.91 |
| InChIKey | RCUWIJNSWOFTSK-CYFMCQSESA-N |
| SMILES | CCC(C)C(C(CC(=O)N1CCCC1C(OC)C(C)C(=O)NC(C)C(O)c1ccccc1)OC)N(C)C(=O)C(NC(=O)C(C(C)C)N(C)C(=O)OCc1ccc(NC(=O)C(CCCNC(N)=O)NC(=O)C(NC(=O)CCOCCOCCOCCOCCNC(=O)OC2CCC=CCCC2)C(C)C)cc1)C(C)C |