dTAG-47

Modify Date: 2024-04-06 11:47:31

dTAG-47 Structure
dTAG-47 structure
Common Name dTAG-47
CAS Number 2265886-81-3 Molecular Weight 1076.24
Density N/A Boiling Point N/A
Molecular Formula C59H73N5O14 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of dTAG-47


dTAG-47, heterobifunctional dTAG molecule, targets mutant FKBP12 (FKBP12F36V). FKBP12F36V serves as a degradation tag (dTAG) and is fused to a protein of interest. dTAG-47 can be used for the research of basal-like breast cancers (BBC)[1].

 Names

Name dTAG-47

 dTAG-47 Biological Activity

Description dTAG-47, heterobifunctional dTAG molecule, targets mutant FKBP12 (FKBP12F36V). FKBP12F36V serves as a degradation tag (dTAG) and is fused to a protein of interest. dTAG-47 can be used for the research of basal-like breast cancers (BBC)[1].
Related Catalog
References

[1]. Hai-Tsang Huang, et al. MELK is not necessary for the proliferation of basal-like breast cancer cells. Elife. 2017 Sep 19;6:e26693.

 Chemical & Physical Properties

Molecular Formula C59H73N5O14
Molecular Weight 1076.24
InChIKey OQXAQHQPOQLCAE-ODPQSFPTSA-N
SMILES CCC(C(=O)N1CCCCC1C(=O)OC(CCc1ccc(OC)c(OC)c1)c1ccccc1OCC(=O)NCCCCCCCCNc1ccc2c(c1)C(=O)N(C1CCC(=O)NC1=O)C2=O)c1cc(OC)c(OC)c(OC)c1
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