Methyltetrazine-PEG4-azide

Modify Date: 2024-01-29 09:35:34

Methyltetrazine-PEG4-azide Structure
Methyltetrazine-PEG4-azide structure
Common Name Methyltetrazine-PEG4-azide
CAS Number 1802908-04-8 Molecular Weight 389.41
Density N/A Boiling Point N/A
Molecular Formula C17H23N7O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Methyltetrazine-PEG4-azide


Methyltetrazine-Ph-PEG4-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Methyltetrazine-Ph-PEG4-azide

 Methyltetrazine-PEG4-azide Biological Activity

Description Methyltetrazine-Ph-PEG4-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C17H23N7O4
Molecular Weight 389.41