(R)-2-Acetamido-3-(1H-indol-3-yl)propanoic acid

Modify Date: 2025-08-25 22:54:18

(R)-2-Acetamido-3-(1H-indol-3-yl)propanoic acid Structure
(R)-2-Acetamido-3-(1H-indol-3-yl)propanoic acid structure
Common Name (R)-2-Acetamido-3-(1H-indol-3-yl)propanoic acid
CAS Number 2280-01-5 Molecular Weight 246.262
Density 1.3±0.1 g/cm3 Boiling Point 586.6±45.0 °C at 760 mmHg
Molecular Formula C13H14N2O3 Melting Point 186ºC
MSDS Chinese USA Flash Point 308.6±28.7 °C

 Names

Name N-acetyl-D-tryptophan
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 586.6±45.0 °C at 760 mmHg
Melting Point 186ºC
Molecular Formula C13H14N2O3
Molecular Weight 246.262
Flash Point 308.6±28.7 °C
Exact Mass 246.100449
PSA 82.19000
LogP 0.70
Vapour Pressure 0.0±1.7 mmHg at 25°C
Index of Refraction 1.645
InChIKey DZTHIGRZJZPRDV-GFCCVEGCSA-N
SMILES CC(=O)NC(Cc1c[nH]c2ccccc12)C(=O)O
Storage condition −20°C

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2933990090

 Synthetic Route

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(R)-2-Acetamido-3-(1H-indol-3-yl)propanoic acid Structure

(R)-2-Acetamido...

CAS#:2280-01-5

Literature: Journal of Organic Chemistry, , vol. 49, # 13 p. 2502 - 2504

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(R)-2-Acetamido-3-(1H-indol-3-yl)propanoic acid Structure

(R)-2-Acetamido...

CAS#:2280-01-5

Literature: US2797226 , ; Bulletin de la Societe Chimique de France, , p. 906

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(R)-2-Acetamido-3-(1H-indol-3-yl)propanoic acid Structure

(R)-2-Acetamido...

CAS#:2280-01-5

Literature: Enzymol., , vol. 14, p. 128,131 US2511867 , ; DRP/DRBP Org.Chem. DE814296 , ;

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(R)-2-Acetamido-3-(1H-indol-3-yl)propanoic acid Structure

(R)-2-Acetamido...

CAS#:2280-01-5

Literature: Stella, Selvaraj; Chadha, Anju Tetrahedron Asymmetry, 2010 , vol. 21, # 4 p. 457 - 460

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(R)-2-Acetamido-3-(1H-indol-3-yl)propanoic acid Structure

(R)-2-Acetamido...

CAS#:2280-01-5

Literature: Journal of the American Chemical Society, , vol. 73, p. 3223,3227

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(R)-2-Acetamido-3-(1H-indol-3-yl)propanoic acid Structure

(R)-2-Acetamido...

CAS#:2280-01-5

Literature: Enzymol., , vol. 14, p. 128,131 US2511867 , ; DRP/DRBP Org.Chem. DE814296 , ;

~%

(R)-2-Acetamido-3-(1H-indol-3-yl)propanoic acid Structure

(R)-2-Acetamido...

CAS#:2280-01-5

Literature: Journal of Biological Chemistry, , vol. 96, p. 511,512, 514

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(R)-2-Acetamido-3-(1H-indol-3-yl)propanoic acid Structure

(R)-2-Acetamido...

CAS#:2280-01-5

Literature: Bulletin of the Agricultural Chemical Society of Japan, , vol. 21, p. 62,64 Journal of Biological Chemistry, , vol. 189, p. 447,458,459

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(R)-2-Acetamido-3-(1H-indol-3-yl)propanoic acid Structure

(R)-2-Acetamido...

CAS#:2280-01-5

Literature: Canadian Journal of Chemistry, , vol. 69, # 7 p. 1124 - 1130

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Bioassay

View more

Name: Primary cell-based high-throughput screening assay for identification of compounds th...
Source: Johns Hopkins Ion Channel Center
Target: regulator of G-protein signaling 4 isoform 2 [Homo sapiens]
External Id: JHICC_RGS_Act_HTS
Name: Luminescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: mu-type opioid receptor isoform MOR-1 [Homo sapiens]
External Id: OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN
Name: QFRET-based biochemical primary high throughput screening assay to identify exosite i...
Source: The Scripps Research Institute Molecular Screening Center
Target: disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens]
External Id: ADAM17_INH_QFRET_1536_1X%INH PRUN
Name: Fluorescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_AG_FLUO8_1536_1X%ACT PRUN
Name: uHTS identification of small molecule activators of the adaptive arm of the Unfolded ...
Source: Burnham Center for Chemical Genomics
Target: N/A
External Id: BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay
Name: Fluorescence polarization to screen for inhibitor that competite the binding of FadD2...
Source: Broad Institute
Target: FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE)
External Id: 2147-01_Inhibitor_SinglePoint_HTS_Activity
Name: Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfect...
Source: Broad Institute
Target: N/A
External Id: Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfected HEK293 cells Inhibition - 7011-01_Antagonist_SinglePoint_HTS_Activity
Name: Fluorescence-based cell-based primary high throughput screening assay to identify pos...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_PAM_FLUO8_1536_1X%ACT PRUN
Name: Fluorescence polarization-based biochemical high throughput primary assay to identify...
Source: The Scripps Research Institute Molecular Screening Center
Target: RecName: Full=Sialate O-acetylesterase; AltName: Full=H-Lse; AltName: Full=Sialic acid-specific 9-O-acetylesterase; Flags: Precursor [Homo sapiens]
External Id: SIAE_INH_FP_1536_1X%INH PRUN
Name: Absorbance-based primary biochemical high throughput screening assay to identify acti...
Source: The Scripps Research Institute Molecular Screening Center
Target: caspase-3 preproprotein [Homo sapiens]
External Id: PROCASPASE3_ACT_EPIABS_1536_1X%ACT PRUN
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 Synonyms

AmbotzAAA1932
MFCD00065021
UNII:4460NBV53F
N-Acetyltryptophan
(R)-2-Acetamido-3-(1H-indol-3-yl)propanoic acid
D-Tryptophan,N-acetyl
EINECS 218-912-4
N-Acetyl-Trp-OH
Ac-D-Trp-OH
Ac-D-tryptophan
N-Acetyl-D-tryptophan
2-(acetylamino)-3-(1H-indol-3-yl)propanoic acid
N-Acetyl-DL-tryptophan
Nb-acetyl-D-tryptophan
(2R)-2-acetamido-3-(1H-indol-3-yl)propanoic acid
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