Bobcat 339

Modify Date: 2025-08-27 23:57:11

Bobcat 339 Structure
Bobcat 339 structure
Common Name Bobcat 339
CAS Number 2280037-51-4 Molecular Weight 297.742
Density N/A Boiling Point N/A
Molecular Formula C16H12ClN3O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Bobcat 339


Bobcat339 (Bobcat 339) is a novel cytosine-based TET enzyme inhibitor with IC50 of 33 uM (TET1) and 73 uM (TET2), but not DNMT3a, does not inhibit the DNA methyltransferase DNMT3a; Bobcat339 is a useful tool for investigation of epigenetics and serve as a starting point for new therapeutics that target DNA methylation and gene transcription.

 Names

Name Bobcat339

 Bobcat 339 Biological Activity

Description Bobcat339 (Bobcat 339) is a novel cytosine-based TET enzyme inhibitor with IC50 of 33 uM (TET1) and 73 uM (TET2), but not DNMT3a, does not inhibit the DNA methyltransferase DNMT3a; Bobcat339 is a useful tool for investigation of epigenetics and serve as a starting point for new therapeutics that target DNA methylation and gene transcription.
References References 1. Chua GNL, et al. ACS Med Chem Lett. 2019 Jan 31;10(2):180-185. View Related Products by Target DNA Methyltransferase (DNMT)

 Chemical & Physical Properties

Molecular Formula C16H12ClN3O
Molecular Weight 297.742
InChIKey QMGYGOOYCNTEQO-UHFFFAOYSA-N
SMILES Nc1nc(=O)n(-c2cccc(-c3ccccc3)c2)cc1Cl
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