PI3K-IN-30

Modify Date: 2024-01-09 18:58:32

PI3K-IN-30 Structure
PI3K-IN-30 structure
Common Name PI3K-IN-30
CAS Number 2281803-22-1 Molecular Weight 449.45
Density N/A Boiling Point N/A
Molecular Formula C20H25F2N7O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of PI3K-IN-30


PI3K-IN-30 (compound 6d) is a potent PI3K inhibitor with IC50s of 5.1, 136, 30.7 and 8.9 nM for PI3Kα, PI3Kβ, PI3Kγ and PI3Kδ, respectively[1].

 Names

Name PI3K-IN-30

 PI3K-IN-30 Biological Activity

Description PI3K-IN-30 (compound 6d) is a potent PI3K inhibitor with IC50s of 5.1, 136, 30.7 and 8.9 nM for PI3Kα, PI3Kβ, PI3Kγ and PI3Kδ, respectively[1].
Related Catalog
Target

PI3Kα:5.1 nM (IC50)

PI3Kβ:136 nM (IC50)

PI3Kγ:30.7 nM (IC50)

PI3Kδ:8.9 nM (IC50)

References

[1]. Van Dort ME, et al. Structural effects of morpholine replacement in ZSTK474 on Class I PI3K isoform inhibition: Development of novel MEK/PI3K bifunctional inhibitors. Eur J Med Chem. 2022;229:113996.

 Chemical & Physical Properties

Molecular Formula C20H25F2N7O3
Molecular Weight 449.45
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