CXCR4 antagonist 8

Modify Date: 2024-01-11 17:50:52

CXCR4 antagonist 8 Structure
CXCR4 antagonist 8 structure
Common Name CXCR4 antagonist 8
CAS Number 2304750-84-1 Molecular Weight 362.47
Density N/A Boiling Point N/A
Molecular Formula C21H26N6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of CXCR4 antagonist 8


CXCR4 antagonist 8 (Compound 3) is a CXCR4 antagonist with an IC50 of 57 nM. CXCR4 antagonist 8 inhibits CXCL12 induced cytosolic calcium increase with an IC50 of 0.24 nM. CXCR4 antagonist 8 inhibits CXLC12/CXCR4 mediated cell migration[1].

 Names

Name CXCR4 antagonist 8

 CXCR4 antagonist 8 Biological Activity

Description CXCR4 antagonist 8 (Compound 3) is a CXCR4 antagonist with an IC50 of 57 nM. CXCR4 antagonist 8 inhibits CXCL12 induced cytosolic calcium increase with an IC50 of 0.24 nM. CXCR4 antagonist 8 inhibits CXLC12/CXCR4 mediated cell migration[1].
Related Catalog
Target

CXCR4:57 nM (IC50)

References

[1]. Lin Y, et al. Design, synthesis, and evaluation of novel CXCR4 antagonists based on an aminoquinoline template. Bioorg Chem. 2020 Jun;99:103824.

 Chemical & Physical Properties

Molecular Formula C21H26N6
Molecular Weight 362.47
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