Pomalidomide-C2-NH2 hydrochloride

Modify Date: 2024-01-12 14:29:18

Pomalidomide-C2-NH2 hydrochloride Structure
Pomalidomide-C2-NH2 hydrochloride structure
Common Name Pomalidomide-C2-NH2 hydrochloride
CAS Number 2305369-00-8 Molecular Weight 352.77
Density N/A Boiling Point N/A
Molecular Formula C15H17ClN4O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Pomalidomide-C2-NH2 hydrochloride


E3 ligase Ligand 17 hydrochloride is a ligand for E3 ubiquitin ligase. E3 ligase Ligand 17 hydrochloride can be connected to the ligand for protein by a linker to form PROTACs. PROTACs are inducers of ubiquitination-mediated degradation of cancer-promoting proteins[1].

 Names

Name E3 ligase Ligand 17 hydrochloride

 Pomalidomide-C2-NH2 hydrochloride Biological Activity

Description E3 ligase Ligand 17 hydrochloride is a ligand for E3 ubiquitin ligase. E3 ligase Ligand 17 hydrochloride can be connected to the ligand for protein by a linker to form PROTACs. PROTACs are inducers of ubiquitination-mediated degradation of cancer-promoting proteins[1].
Related Catalog
Target

Cereblon

References

[1]. Shibata N, et al. Development of Protein Degradation Inducers of Androgen Receptor by Conjugation of Androgen Receptor Ligands and Inhibitor of Apoptosis Protein Ligands. J Med Chem. 2018 Jan 25;61(2):543-575.

 Chemical & Physical Properties

Molecular Formula C15H17ClN4O4
Molecular Weight 352.77